Subject(s)
Humans , Male , Adolescent , Weil Disease/complications , Weil Disease/diagnosis , Weil Disease/drug therapy , Weil Disease/diagnostic imaging , Shock, Septic/diagnosis , Zoonoses/epidemiology , Diagnosis, Differential , Fever/diagnosis , Leptospira interrogans/isolation & purification , Anti-Bacterial Agents/therapeutic useABSTRACT
A total of 2400 patients with pyrexia of unknown origin and or suspected leptospirosis were included in this study. Dark field microscopy detected Leptospira in 690 cases, Leptospira serological Investigations proved positive in 570 out of these 690 patients. Among them 212 had the classical icteric and the other 358 had anicteric type of presentation. Notably eptospira interrogans serovar ictero haemorrhagiae infection was encountered in 212 patients. In 30 patients, who had multi organ dysfunction which included renal failure, hepatic dysfunction or meningitis was due to Leptospira interrogans Serovar cannicola. Coexsistense of leptospirosis and hepatitis B virus infection were noted in 15 patients. Antibody to Leptospira interrogans was demonstrated by Micro agglutination test (MAT) in addition to dark field microscopy positivity in these cases. Similarly HIV antibody was demonstrated in 30 of the 330 anicteric patients. 554 out of 570 cases responded to intra venous penicillin (216), and oral Doxycycline (182) and Augmentin (156), and the remaining 16 patients succumbed to death.
Subject(s)
Adolescent , Adult , Aged , Animals , Child , Child, Preschool , Female , Humans , Leptospira/classification , Leptospira interrogans/classification , Leptospirosis/drug therapy , Male , Middle Aged , Multiple Organ Failure/microbiology , Prevalence , Weil Disease/drug therapy , ZoonosesABSTRACT
Presentamos el caso de una mujer de 29 años, de un sector subnormal de Neiva con un cuadro de fiebre, dolores musculares, ictericia, hemorragia de vías digestivas, sin compromiso hemodinámico y falla renal aguda. La M.A.T. fue positiva para 4 serovars con títulos mayores de 1/800 diluciones. Este es uno de los pocos casos informados en la literatura, causada por múltiples serovars.